Team

UNICA

Gaetano Di Chiara

Principal Investigator – WP 1 Leader

Emeritus Professor of Pharmacology

University of Cagliari

Curriculum
Curriculum

Gaetano Di Chiara is Emeritus Professor of Pharmacology at the University of Cagliari. After the degree in Medicine and Surgery at the University of Cagliari, Italy, he spent three years as a postdoctoral fellow in the Laboratory of Chemical Pharmacology (National Institutes of Health at Bethesda, Maryland, USA) where he developed a rat model of human drug-induced hemolysis.

Back in Italy, he got a permanent position as Assistente di ruolo to the chair of Pharmacology of the University of Cagliari and was charged of the teaching of Toxicology and Pharmacology in the medical school. In 1980 he was appointed Full Professor of Pharmacology and Toxicology in the medical school and in 1983 was called to teach Pharmacology and Pharmacognosy in the Faculty of Pharmacy, serving as Dean of the same Faculty from 1997 to 2006.

Professor Di Chiara has been President of the National Pharmacy Faculty Deans Conference, of the European Behavioural Pharmacology Society (EBPS), of the Federation of the European Neuroscience Societies (FENS) and of the Italian Society of Neuroscience (SINS). According to ISI (Institute for Scientific Information) of Philadelphia (USA), he is among the most cited researchers in the fields of Neuroscience and Pharmacology. His research is focused on drugs that affect the central nervous system and on the neurotransmitter mechanism of drug-addiction.

Maria Antonietta De Luca

Coordinator Assistant – WP4 Leader

Researcher – Neuroscience Unit

Department of Biomedical Sciences

University of Cagliari

Curriculum
Curriculum

Dr Maria Antonietta De Luca is a Researcher at the Neuroscience Unit of the Department of Biomedical Sciences, University of Cagliari (Italy).

After an MSc in Chemistry and Pharmaceutical Technology, she completed a Specialization in Toxicology and a PhD in Pharmacology of Drug Abuse at the University of Cagliari, supervised by Prof. Gaetano Di Chiara. In her career she has developed a strong expertise in the field of the neurochemistry and behavioural pharmacology, with a major focus on the role of mesolimbic and mesocortical dopaminergic transmission in the origin of drug addiction. She has over 15 years of experience with in vivo microdialysis in rodents for monitoring brain monoamines following the administration of drugs of abuse and natural rewards.

She also has a wider knowledge on animal models of drug addiction with particular reference to the rewarding properties of cannabinoids and endocannabinoids, and novel psychoactive substances (NPS). Her knowledge in this research field has improved in 2002–2004 spending several months as a Guest Researcher at the National Institutes on Drug Abuse (NIDA) in Baltimore (MD, USA) in the team of Dr. S.R. Goldberg.

In 2014, she completed a Fulbright Research Scholar activity as a Visiting Scientist at the Committee on Neurobiology of Addictive Disorders of the Scripps Research Institute (TSRI, La Jolla, CA, USA). At TSRI, she joined the team of Dr. L.H. Parsons for studying the addictive properties of synthetic marijuana (i.e. JWH-018) and the genetic predisposition toward cannabinoid addiction. In the past years, she was a member of the EU-MADNESS team for looking at Novel Psychoactive Substances (NPS).

She is currently PI of two National Research Project investigating the pharmacological characterization of NPS and Coordinator Assistant of JUSTSO project.

Maria Paola Castelli

Researcher – Neuroscience Unit

Department of Biomedical Sciences

University of Cagliari

Curriculum
Curriculum

Dr. M. Paola Castelli is a Researcher at the Neuroscience Unit of the Department of Biomedical Sciences, University of Cagliari (Italy).

After a degree in Medicine, she completed a Specialization in Obstetrics and Gynecology, a PhD in Immunology and a Specialization in Pharmacology at the University of Cagliari under the supervision of Prof. Gian Luigi Gessa.

From 1986 till 1994, she carried out her research at the Department of Immunology, National Cancer Institute of Frederick (NCI-FCRF, USA) and at the Mario Negri Sud Research Institute where she investigated the immunoregulatory properties of cytokines, beta-adrenergic agonists and factors of “thyroid-specific” gene transcription of the TSH receptor. Since 1994, the focus of her research has been on the investigation of different neurobiological mechanisms which underlie behavioral, cognitive and emotional functions, through the investigation of several neurotransmitters, their receptors and their mechanisms of action, such as biological- and physiological- correlates of the Central Nervous System.

Furthermore, since one of her major interests is the study of neurobiology of drug abuse, for the past 20 years she has been involved in research projects investigating molecular and biochemical mechanisms of drugs of abuse, with particular attention paid to the GABAB receptor and the role of CB1 receptors in drug addiction and polydrug abuse.

She has over 20 years’ experience in biochemical pharmacology and neurochemistry, with a major focus on neurochemical mechanisms in the origin of drug addiction. As PI or co-investigator in several projects funded by MIUR- (Italian Ministry of Education, University and Research, Italy) or by private foundations, she has contributed to clarify the involvement of the endocannabinoid system and CB1 receptors in both physiological conditions and neuropsychiatric disorders, including eating and mood disorders.

Graziella Tocco

Assistant Professor in Organic Chemistry

Faculty of Biology and Pharmacy

University of Cagliari

Curriculum
Curriculum

Dr. Graziella Tocco is Assistant Professor in Organic Chemistry at the Faculty of Biology and Pharmacy at the University of Cagliari (UNICA), where, since 2002, she teaches Organic Chemistry.

In 1995 she took a degree in Chemistry and Pharmaceutical Technology and then a Ph.D. in Technology and Legislation of Drugs and Bioactive Molecules, spending a period as Ph.D. visiting scholar at Faculty of Chemistry-University of Milan (Prof. M. Cinquini and F. Cozzi).

As winner of a “Young Researchers Project” grant, she worked with Prof. M. Benaglia as Post Doc visiting scholar at the University of Milan, gaining expertise in Liquid Phase PEG-supported synthesis of heterocyclic derivatives for catalytical and pharmaceutical application.

Since 2002, her area of expertise is organic and medicinal chemistry mainly focused on the design, the synthesis, the NMR characterization and the development of new drug -like molecules. In particular, within the framework of a collaboration with Prof. Stuart F.J. Le Grice (National Cancer Institute, Frederick, U.S.A.), she works on the design, synthesis and SAR study of novel pyrimidinone-like molecules as allosteric inhibitors of HIV­1 Reverse Transcriptase Associated Ribonuclease H.

In 2010 she started a collaboration with Prof. M. Ciufolini (British Columbia University (UBC)- Vancouver, Canada) that gave rise to a Cooperation Agreement between UNICA and UBC. In 2015, as winner of a Fulbright Research Scholar Grant, she worked with Prof. J. Fuchs and Prof. M. Kvaratskelia at the College of Pharmacy of Ohio State University (OSU), on a project directed toward the chemical structure optimization and synthesis of some thienopyrimidinone hit compounds and the elucidation of their mode of action as allosteric inhibitors of HIV-1 integrase.

Besides, since 2016, she is coordinator of a Cooperation Agreement between UNICA- Faculty of Biology and Pharmacy and OSU- College of Pharmacy.

Pierluigi Caboni

Professor of Food Chemistry and Analytical Chemistry

Department of Life and Environmental Sciences

University of Cagliari

Curriculum
Curriculum

B.S. (Bachelor’s degree) in Chemistry, University of Cagliari, Italy. The last year experimental work was carried on the “Pseudo-humic substances obtained from urban waste” under the supervision of Prof. G. Alberti.

M.S. degree in Chemistry, University of Cagliari, Italy. Research on soil analysis and environmental pollution at the Department of Chemical Sciences under the supervision of Prof. G. Alberti.

PhD in Pathology and Environmental Toxicology, University of Cagliari, Italy. Thesis title “Naturally Occurring Pesticides”. The research project included the development of new analytical methods for the determination of pesticides (carried out at the University of Cagliari under the supervision of Prof. P. Cabras) and the study of the toxicology aspects (carried out at the University of California at Berkeley under the supervision of Prof. J. E. Casida).

Post-doc position at the University of California, Berkeley, in the Environmental Chemistry and Toxicology Laboratory under the supervision of Prof. J.E. Casida.

The research activity is focused on drug metabolism and molecular toxicology.

From 2005 to 2014, Professor of FOOD CHEMISTRY at the University of Cagliari, Italy. in the High Resolution Mass Spectrometry Laboratory, Department of Life and Environmental Sciences.

Nowadays he’s Professor of FOOD CHEMISTRY and ANALYTICAL CHEMISTRY at the University of Cagliari, Italy, in the High Resolution Mass Spectrometry Laboratory, Department of Life and Environmental Sciences. The research activity is focused on plant omics, food analysis, pesticide and drug metabolism, metabolomics.

FP7 Funded projects: Partner -ACTION 2013-12-19 THEME HEALTH.2013.2.2.1-3Project full title: Aggression in children: unraveling gene-environment interplay to inform treatment and intervention strategy, GRANT NO602768

Expertise and Analytical skills: Protein and metabolites characterization by mass spectrometry. Metabolomics and Proteomics. High and low resolution mass spectrometry. Chemical characterization of food,  biologicl and environmental matrices. Analytical platforms: nanoLC-MS-ESI-QTOF, LC/MS/MS, HPLC, GC/MS, Ion mobility LCTOFMS.

CEO  of the Academic spin-off Toxmed srl.

Member of the: American Chemical Society (ACS), Italian Forensic Toxicologist Association, Italian Chemist Association.

Rafaela Mostallino

Fellowship

Neuroscience and Clinical Pharmacology Division

Department of Biomedical Sciences

University of Cagliari

Curriculum
Curriculum

Fellowship for the project “Analysis, knowledge dissemination, JUstice implementation and Special Testing of novel Synthetic Opioids (JUSTSO)” at the Neuroscience and Clinical Pharmacology Division of the Department of Biomedical Sciences, University of Cagliari (Italy).

She graduated in Experimental Biology (July 2016) and in Neuropsycobiology (September2018) at the University of Cagliari, Italy.  During these years she has investigated the expression of GABA-A receptor and its subunits in physiological and pathophysiological conditions utilizing different techniques (i.e., western blot,  immunohistochemical analysis). In addition, she  has evaluated the density and morphology of dendritic spines and analyzed the dendritic tree complexity by Golgi staining in different rat brain areas.

Since January 2019, under the supervision of Dr. M. Paola Castelli, she is evaluating the affinity and the intrinsic activity of Novel Synthetic Opioids (NSO) for the different types of opioid receptors  (MOR, DOR, KOR). She is studying the pharmacological in vitro effects of ad hoc synthesized potential opioid agonists/ antagonists on their biological targets (MOR and DOR). Specifically, she is investigating the affinity (Ki),  potency (EC50) and Emax (efficacy) of these new compounds by performing in vitro and ex vivo studies using different techniques, such as receptor radioligand and GTPγS binding assay, both in native tissue and in CHO-cells expressing opioid receptors.

UDA

Giovanni Martinotti

Associate Professor of Psychiatry

University Gabriele D’Annunzio

Curriculum
Curriculum

Prof. Giovanni Martinotti, M.D., PhD in “Methodology and advanced research in psychopathology and psychotherapy”, Associate Professor of Psychiatry.

He is the Acadamic Lead of the research unit on Addiction and Addictive Behaviours. In his career, he has developed a strong clinic and academic expertise in the field of substance abuse, as well as other forms of addiction including pathologic gambling and behavioural addictions; his main research focuses were related pharmacological and non-pharmacological treatment options for addicted patients, dual diagnosis and personality traits.

He has been involved in multiple international research projects, related in particular to novel psychoactive substances. He is also associate editor of different scientific journals.

He is currently president of the Young Section of the Italian Society of Psychiatry. He has a current H-index of 40, 244 published documents and a total of 4367 citations (source: Scopus database).

IMIM

Marta Torrens

Head of Addiction Section

Institut de Neuropsiquiatría i Adiccions – INAD of Parc de Salut Mar

Associate Professor at Psychiatry and Legal Medicine Department

Universitat Autonoma de Barcelona

Curriculum
Curriculum

Head of Addiction Section at the Institut de Neuropsiquiatría i Adiccions – INAD of Parc de Salut Mar, Barcelona.

Associate Professor at Psychiatry and Legal Medicine Department at Universitat Autonoma de Barcelona, Barcelona.

Coordinator of the Grup de Investigació en Adiccions (GRAd), Institut Hospital del Mar d’Investigacions Mèdiques – IMIM, Parc de Recerca Biomèdica de Barcelona – PRBB, Barcelona.

Maria Alias

Research collaborator

Institut Hospital del Mar d’Investigacions Mèdiques

Curriculum
Curriculum

Researcher in Grup de Investigació en Adiccions (GRAd), Institut Hospital del Mar d’Investigacions Mèdiques – IMIM, Parc de Recerca Biomèdica de Barcelona – PRBB, Barcelona.

 

Claudio Castillo

Research collaborator

Institut Hospital del Mar d’Investigacions Mèdiques

Curriculum
Curriculum

Psychiatry in Addiction Section at the Institut de Neuropsiquiatría i Adiccions – INAD of Parc de Salut Mar, Barcelona.

Researcher in Grup de Investigació en Adiccions (GRAd), Institut Hospital del Mar d’Investigacions Mèdiques – IMIM, Parc de Recerca Biomèdica de Barcelona – PRBB, Barcelona.

Francina Fonseca

Research collaborator

Institut Hospital del Mar d’Investigacions Mèdiques

Associate Professor

Psychiatry and Legal Medicine Department

Universitat Autonoma de Barcelona

Curriculum
Curriculum

Psychiatry in Addiction Section at the Institut de Neuropsiquiatría i Adiccions – INAD of Parc de Salut Mar, Barcelona.

Associate Professor at Psychiatry and Legal Medicine Department at Universitat Autonoma de Barcelona, Barcelona.

Researcher in Grup de Investigació en Adiccions (GRAd), Institut Hospital del Mar d’Investigacions Mèdiques – IMIM, Parc de Recerca Biomèdica de Barcelona – PRBB, Barcelona.

Joana Kyra València

Associate Clinical Psychologist – Research collaborator

Institut Hospital del Mar d’Investigacions Mèdiques

Curriculum
Curriculum

Associate Clinical Psychologist in Addiction Section at the Institut de Neuropsiquiatría i Adiccions – INAD of Parc de Salut Mar, Barcelona.

Researcher in Grup de Investigació en Adiccions (GRAd), Institut Hospital del Mar d’Investigacions Mèdiques – IMIM, Parc de Recerca Biomèdica de Barcelona – PRBB, Barcelona.

UNIVPM

Raffaele Giorgetti

WP 3 – Leader

Full Professor in Legal Medicine

Marche Polytechnic University

Curriculum
Curriculum

Professor Raffaele Giorgetti holds the degree of Full Professor in Legal Medicine at the Università Politecnica della Marche, Italy.

He is author of more than 150 papers published in the following subjects: forensic toxicology, forensic genetics, forensic pathology, professional medical malpractice, public health care, social assistance and professional regulations.

Professor Giorgetti studies NPS and conventional drugs, drinking and driving, driving under influence, psychomotor performance.

He is member of The International Association of Forensic Toxicologists (TIAFT).

 

Francesco Paolo Busardò

Associate Professor of Forensic Science and Toxicology

University “Politecnica delle Marche”

Curriculum
Curriculum

Prof. Busardò obtained in 2009 his Degree with honor in Medicine and Surgery at the University of Palermo (Italy), winning the Prize for the Best Thesis.

In 2014, he received a Diploma in Forensic and Medical Sciences from The Worshipful Society of Apothecaries of London.

In 2015 he specialized in Forensic Medicine at “Sapienza” University of Rome, Italy with maximum marks (70/70 cum laude).

In 2015 he obtained a MSc in Forensic Toxicology at the University of Glasgow, Scotland. UK.

In 2017 he obtained a PhD in Legal Medicine and Forensic Sciences at “Sapienza” University of Rome, Italy with maximum marks.

From March 2018 he is Adjunct Professor of Forensic Science and Toxicology and lead forensic toxicologist at Sapienza University of Rome, Italy.

From July 2018 he is Associate Professor of Forensic Science and Toxicology at University “Politecnica delle Marche” of Ancona, Italy.

UKESSEN

Norbert Scherbaum

Director of the Department of Addictive Behaviour and Addiction Medicine

Director of the Department for Psychiatry and Psychotherapy at the LVR-Hospital Esse

University Duisburg-Essen

Curriculum
Curriculum

Professor Norbert Scherbaum is the Director of the Department of Addictive Behaviour and Addiction Medicine as well as of the Department for Psychiatry and Psychotherapy at the LVR-Hospital Essen, University Duisburg-Essen.

His research focuses in the field of opiate dependence include evaluation of opiate detoxification treatments, novel interventions, the assessment and treatment of comorbid disorders and diseases, improvement of opioid maintenance treatment, and evaluation of drug consumption rooms.

He participated in several EU-funded projects regarding New Psychoactive Substances, e.g. PSYCHONAUT, ReDNet and EU-MADNESS. He also is a member of the Committee for Drugs and Narcotics (Ausschuss für Betäubungsmittel) at the Federal Ministry of Health (Bundesministerium für Gesundheit) and of the Committee for Addiction and Drugs (Ausschuss für Sucht und Drogen) at the German Medical Association (Bundesärztekammer)

Michael Specka

Researcher

Department of Addictive Behaviour and Addiction Medicine

University Duisburg-Essen

Curriculum
Curriculum

Michael Specka is a psychologist and researcher at the university of Duisburg-Essen, Germany, Department of Addictive Behaviour and Addiction Medicine.

He has been conducting and publishing research in the field of substance dependence for over 20 years now.

His main focus is on prevention and treatment of harmful use of psychotropic substances, especially opioids.

Henning Hafermann

 

University Duisburg-Essen

Curriculum
Curriculum

Henning Hafermann is a medical student in the clinical part of his studies at the University of Duisburg-Essen, Germany.

For several years he has been working for the LVR-Hospital Essen – Hospital and Institute of the University Duisburg-Essen –

Department of Psychiatry and Psychotherapy, Essen, Germany. He has been involved in research projects in the field of the Alzheimer‘s disease and is responsible for maintaining the department’s biological materials repository.

A few years ago, he also started to support the researcher team of the Department of Addictive Behaviour and Addiction Medicine.

UNED

Emilio Ambrosio

Full Professor of Psychobiology

National University for Distance Learning

Curriculum
Curriculum

Emilio Ambrosio is Full Professor of Psychobiology at the National University for Distance Learning (UNED) in Madrid, Spain.

He obtained two different Bachelor Degrees,  Biological Sciences and Psychology, at the Autonomous University of Madrid in 1979. His PhD was also earned at the same University in 1985 working on sex differences in cerebral alpha-adrenergic receptors. After this period of academic training, he started to work in the field of psychopharmacology testing the role of Corticotropin Releasing Factor (CRF) in animal models of depression, and in 1991 he began to study the psychobiological mechanisms involved in drug addiction as Visiting Professor at National Institute on Drug Abuse (NIDA, Baltimore, USA).

Professor Ambrosio has mainly focused his research in this area on the psychobiological factors that might induce high susceptibility to drugs of abuse, especially psychostimulants and opiates, as well as the interaction between the endocannabinoid system and other neutransmission systems such as the endogenous opioid, dopaminergic, glutamatergic or GABAergic ones, with the aim of studying:

1) the factors that facilitate psychostimulant and opiate self-administration behaviours;

2) the effects that perinatal and peripuberal cannabinoid exposure may have on the acquisition of opiate and psychostimulant self-administration during adulthood;

3) the neuroadaptations that are produced during the maintenance of self-administration behaviour and during its extinction, as possible neuronal correlates of vulnerability to relapse in drug abuse.

He has co-authored numerous scientific articles published in international journal, supervised and  mentored a great number of doctoral thesis, and received several national awards for his contributions to the field of addictive behaviors

Alejandro Higuera-Matas

Research collaborator

National University for Distance Learning

Curriculum
Curriculum

Alejandro Higuera-Matas received his BSc and MSc in Psychology from the University of Granada (Spain) in 2003 and his doctoral degree in Psychology from the National University for Distance Education in Madrid (Spain) in 2008.

He then joined the Department of Pharmacology of the Complutense University in Madrid as a postdoctoral scientist studying the modulation of anxiety, learning and memory by MDMA.

Dr. Higuera-Matas ‘s main research interests are the long-term consequences of adolescent cannabinoid consumption, the interaction between prenatal immune activation and drug exposure as a model of schizophrenia-related symptoms, the psychobiology of impulsive behaviours and the neural mechanisms operating in relapse to drug abuse.

Dr Higuera-Matas has been visiting scholar in many internationally renowned centers such as the University of Cambridge, the Mount Sinai School of Medicine, the Scripps Research Institute, to name just a few. His research combines sophisticated behavioural methods with next-generation sequencing, epigenetic technologies and neuroimaging techniques (MRI and PET) in rats.

Dr Higuera-Matas is coauthor of 39 research papers and reviews in the field of addiction neuroscience, has earned several prizes for his scientific achievements and has mentored students at the Master and Doctorate level.

ISS

Roberta Pacifici

Director of the National Centre on Addiction and Doping

Italian National Institute of Health (Istituto Superiore di Sanità-ISS)

Curriculum
Curriculum

Roberta Pacifici is the Director of the National Centre on Addiction and Doping at the Italian National Institute of Health (Istituto Superiore di Sanità).

She is the research manager of the following areas: National observatory of tobacco, drugs of abuse and alcohol; analytical laboratory on drugs and doping agent in non conventional matrices related to clinical and forensic pharmacotoxicology; epidemiological studies, supervision of analytical laboratory devoted to assays for drugs of abuse in non conventional matrices, smart drugs, dietary supplements.

She is member of the Doping Surveillance and Health Promotion in Sports Activities Section (2003-present) and author of more than 300 scientific publications

Simona Pichini

Unit Head of Analytical Pharmacotoxicology Unit at National Centre on Addiction and Doping

Italian National Institute of Health  (Istituto Superiore di Sanità-ISS)

Curriculum
Curriculum

Doctor in Chemistry and Pharmaceutical Technology, European PhD in Clinical Pharmacology, Unit Head, Analytical Pharmacotoxicology Unit, National Centre on Addiction and Doping, National Institute of Health of Italian (Istituto Superiore di Sanità-ISS)

Emilia Marchei

Researcher in the Analytical Pharmacotoxicology Unit of the National Centre on Addiction and Doping

Italian National Institute of Health  (Istituto Superiore di Sanità-ISS)

Curriculum
Curriculum

Emilia Marchei , degree in Chemistry and Pharmaceutical Technologies, is a researcher in the “Analytical Pharmacotoxicology Unit of the National Centre on Addiction and Doping, Italian National Institute of Health (Istituto Superiore di Sanità-ISS).

Her main activities includemass Spectrometry method development and validation for the purpose of clinical and forensic pharmacotoxicology; epidemiological studies.

She has been involved in studies in the field of drug and alcohol monitoring in conventional and non conventional biological matrices; pharmacokinetics and toxicokinetics of drugs, drugs of abuse, new psychoactive drugs and doping agents.

Author of more than 80 scientific publications.

LIOS

Valerjans Kauss

Head of Laboratory of CNS Active Compounds

Latvian Institute of Organic Synthesis (LIOS)

 

Curriculum
Curriculum

Dr.chem. V.Kauss is the Head of Laboratory of CNS Active Compounds of Latvian Institute of Organic Synthesis (LIOS).

Laboratory was founded in 2001 for projects focused on the development of new medicines for CNS disorders.

Laboratory of V.Kauss is experienced team of chemists familiar with modern organic synthesis and medicinal chemistry approaches in drug discovery and development working in close contacts with pharmacologists.

V.Kauss has experience in management of research group dealing with all stages in the process of CNS drug discovery. Within the long term collaboration between LIOS and Merz Pharmaceuticals, V.Kauss headed the chemistry program for lead identification and optimization of uncompetitive antagonists of NMDA receptors.

He is co-inventor of neramexane, a drug related to memantine and reached phase 3 clinical trials.

Dr. Kauss managed development of the synthesis of all presumptive metabolites of neramexane and elaboration of synthesis procedure appropriate to production conditions. V.Kauss is co-author of more than 30 international patents.

For his achievements he received Award of Prime Minister of Latvian Republic for contribution in the development of medicinal chemistry and education of new specialists (2007). Dr. Kauss manages short lecture course: „Technology of CNS medicines” at Riga Technical University.

He is supervisor of 6 Ph.D. theses, supervisor of many M.Sc. theses at University of Latvia and Riga Technical University.

 

Maksims Vanejevs

principal scientist

Laboratory of CNS Active Compounds

Latvian Institute of Organic Synthesis (LIOS)

 

Curriculum
Curriculum

Maksims Vanejevs graduated Riga Technical University in 2003.

He was twice awarded by national “Education, Science and Culture” programme for students` research as the most successful young scientist in synthesis and chemistry of biologically active ingredients. Then M. Vanejevs got research assistant position at Latvian Institute of Organic Synthesis (LIOS). In paralel to work at LIOS he entered doctoral studies at Riga Technical University Faculty of Material Science and Applied Chemistry.

He received PhD degree (Dr. Chem.) in 2008 after defense of dissertation “Functionalization of C-H bond in cyclohexylamine series”. M. Vanejevs has wide experience in large scale and microscale synthesis of aliphatic and heterocyclic compounds.

He has participated in medicinal chemistry projects in collaboration with pharmaceutical companies, which resulted in a series of patents. Current position – principal scientist at LIOS, Laboratory of CNS active compounds.

 

Anastasija Ture

research scientist

Laboratory of CNS Active Compounds

Latvian Institute of Organic Synthesis (LIOS)

 

Curriculum
Curriculum

Anastasija Ture graduated Riga Technical University in 2006 and received young scientist award of Latvian Academy of Sciences for excelent master`s degree study „Synthesis of the potential metabolites of primary amines – N-glucosides and Amadori products”. Then she started PhD studies at Riga Technical University Faculty of Material Science and Applied Chemistry in Department of Chemistry.

As the result of doctoral research at Latvian Institute of Organic Synthesis, A. Ture presented dissertation “The synthesis of NMDA receptor GlycineB binding site antagonists” in 2011.

Since that event she has participated in several international scientific research projects, mainly, related to medicinal chemistry and targeted to development of new medicines. Currently she is research scientist at Latvian Institute of Organic Synthesis, Laboratory of CNS active compounds.

 AUTH

Georgios Papazisis

WP5 – Leader

Associate Professor of Basic and Clinical Pharmacology

Department of Clinical Pharmacology

School of Medicine

Aristotle University of Thessaloniki

 

Curriculum
Curriculum

Georgios Papazisis MD, PhD, is Associate Professor of Basic and Clinical Pharmacology at the Department of Clinical Pharmacology, School of Medicine of the Aristotle University of Thessaloniki, Greece.

He is a practicing psychiatrist specialized in psychopharmacology and Cognitive – Analytic Psychotherapy. Neuropsychopharmacology, pharmacovigilance (psychotropic drug safety and patient’s safety) and medication errors are his fields of interest.

In 2018 he completed the pharmacovigilance training course at Uppsala Monitoring Centre, the WHO collaborating Centre for international drug monitoring.

Dr. Papazisis is an ad-hoc reviewer of several international journals and has published 44 Pub-Med papers, 72 indexed abstracts and 2 book chapters (In Vivo Neuropharmacology and Neurophysiology, Springer 2017; Neuropathology of Drug Addictions and Substance Misuse, Elsevier 2016). His work has over 1000 citations with an h-index of 21.

He is the principal investigator for Greece for the ‘JUSTSO’ project and for a multicenter clinical trial sponsored by the ECNP (RTOC). He is also the medical advisor in the Horizon 2020 PCP funded project ‘Relief’.

He currently serves as an External Expert for the European Medicines Agency and is also National Representative Observer of the EMA Central Nervous System Working Party. Additionally, he serves as an external expert and clinical assessor for the Pharmacovigilance Department of the Greek National Organization for Medicines.

He is also member of EOF’s Second Degree Scientific Advisory Board and of the National Committee for Illicit Drugs. In June 2018 he became regular member of the National Health Technology Assessment Committee.

Dr. Papazisis is the Treasurer of the Greek Society of Pharmacology and Clinical Pharmacology, member of the ‘Evidence Based Psychiatry’ section of the World Psychiatric Association and active member of ECNP, EACPT, AGNP and ISoP.

Antonis Goulas

Full Professor of Pharmacology

Department of Clinical Pharmacology

School of Medicine

Aristotle University of Thessaloniki

Curriculum
Curriculum

Antonis Goulas MD, PhD is Full Professor of Pharmacology at the 1st Department of Pharmacology, Medical School, Aristotle University of Thessaloniki.

He is also a certified forensic pathologist since 2015.

His main research interests are Pharmacogenetics of cardiovascular and psychotropic drugs and toxigenetics.

Mr Goulas is member of the Scientific Committee of Approvals for Biologics and Blood Products of the Hellenic Drug Organization and Member of the Executive Committee of the Hellenic Society for the Study of Substances of Abuse and the Hellenic Society of Basic and Clinical Pharmacology.

He served in the Dissertation Committees of over 15 PhD candidates of the Medical School and of the Scholl of Dentistry.

His total number of publications (full papers, short communications, review articles, case reports) in English language peer-review journals is 55 (scopus); book chapters: 5; scientific book translations in Greek: 2 (Rang & Dale, Pharmacology; Casarett & Doul, Basic Toxicology) . Total number of citations (SCOPUS): 552, h-index: 15

 ICS

Magì Farré

Head of the Clinical Pharmacology Unit

Hospital Universitari Germans Trias i Pujol (Institut Català de la Salut)

Professor of Pharmacology

School of Medicine

Universitat Autònoma de Barcelona

Curriculum
Curriculum

Magi Farré is medical doctor (MD, PhD) and specialist in Clinical Pharmacology. Actually, he is the Head of the Clinical Pharmacology Unit at Hospital Universitari Germans Trias i Pujol (Institut Català de la Salut) in Badalona and Professor of Pharmacology at the School of Medicine of the Universitat Autònoma de Barcelona.

During the last twenty years has been involved in the study of the human pharmacology of different substances including MDMA, GHB, flunitrazepam, tramadol, cannabis and alcohol and its interactions. In recent years he has been part in different European projects about Novel/New Psychoactive Substances.

The last one is the JUSTSO project.

His recent investigations include the acute pharmacological effects of 2C-B , synthetic cathinones and other psychostimulants, alcohol, synthetic cannabinoids, and new synthetic opioids in humans. In addition he has been interested in the pharmacological treatment of addictions (mainly cocaine, alcohol and cannabis) and the therapeutic use of cannabis and hallucinogen drugs.

 

Esther Papaseit

Assistant Professor of Pharmacology

School of Medicine

Universitat Autonoma of Barcelona (UAB)

Curriculum
Curriculum

Esther Papaseit is medical doctor (MD, PhD) specialist in Clinical Pharmacology and Assistance Professor of pharmacology at the School of medicine of the Universitat Autonoma of Barcelona (UAB). She is member of the Clinical Pharmacology Unit of the Hospital Universitari Germans Trias i Pujol (Institut Català de la Salut) in Badalona.

She specializes in pharmacologic research on drugs of abuse and abuse liability in humans. Her main research work has focused on the study of the human pharmacology drugs of abuse (alcohol, cannabis, nicotine, amphetamines, synthetic cathinones-cannabinoids and other new psychoactive substances).

In recent years she has been collaborate in different projects about Novel/New Psychoactive Substances including the JUSTSO project.

 

Clara Pérez-Mañá

Assistant Professor of Pharmacology

School of Medicine

Universitat Autonoma of Barcelona (UAB)

Curriculum
Curriculum

Clara Pérez-Mañá MD, PhD, Clinical pharmacologist, Assistant Professor of Pharmacology at the School of Medicine of the Universitat Autònoma de Barcelona.

She is senior consultant at the Clinical Pharmacology Unit of the Hospital Universitari Germans Trias i Pujol in Badalona. Her main research interests focus on the study of the human pharmacology of different drugs of abuse and the interaction between alcohol and energy drinks.

In the last 10 years has collaborated in the execution of more than 30 phase I-II clinical trials. As a clinical pharmacologist has broad background in ethics and research methodology in human beings. She has also conducted several meta-analysis in the field of addiction.

 

Roberto Muga

Professor of Medicine

Hospital Universitari Germans Trias i Pujol

Curriculum
Curriculum

Roberto Muga is Professor of Medicine at Hospital Universitari Germans Trias i Pujol in Badalona, Spain and Faculty at the Department of Internal Medicine/Addiction Unit.

Since 1987, his research interests are related to the medical consequences of alcohol and substance use disorder, including viral infections and liver diseases.

He earned a MPH from Johns Hopkins University (Baltimore, USA) and has been PI in several projects funded by public institutions in Spain (Ministry of Health).

Since 2002, Dr. Muga is PI in RETICS, the Spanish Thematic Network on Addictive Disorders and has also been involved in several projects from the European Union (Sixt and Seventh Framework Programs) (http://www.eurocoord.net/).

Dr Muga has published over 200 peer-reviewed research papers and more than 300 conference communications.

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